The cheapest and fastest coaches from Rome to Brussels
Cheapest price
$171
Average price
$253
Fastest journey
1 d 1 h 10 m
Average duration
1 d 3 h 46 m
Buses per day
11
Distance
1174 km
The best way to find a cheap coach ticket from Rome to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Rome to Brussels will cost around $253 if you buy it on the day, but you can find cheap coach tickets today for only $171.
To travel from Rome to Brussels you need to make at least one change.
4788 · 503273:20 PM25h10Roma, Autostazione Tiburtina4:30 PMBrussels, Brussels South (Gare du Midi)$1711One-way1 change
FlixBus · FlixBus · FlixBus8:00 PM29h10Roma, Autostazione Tiburtina1:10 AMBrussels, Brussels South (Gare du Midi)$2061One-way2 changes
FlixBus · FlixBus · FlixBus10:45 PM28h20Roma, Autostazione Tiburtina3:05 AMBrussels, Brussels South (Gare du Midi)$2071One-way2 changes
FlixBus · FlixBus · FlixBus10:55 PM32h25Roma, Autostazione Tiburtina7:20 AMBrussels, Brussels South (Gare du Midi)$2181One-way2 changes
FlixBus · FlixBus · FlixBus10:40 AM31h15Roma, Autostazione Tiburtina5:55 PMBrussels, Brussels South (Gare du Midi)$2521One-way2 changes
4788 · 503273:20 PM25h10Roma, Autostazione Tiburtina4:30 PMBrussels, Brussels South (Gare du Midi)$1711One-way1 change
FlixBus · FlixBus8:50 AM27h55Roma, Autostazione Tiburtina12:45 PMBrussels, Brussels South (Gare du Midi)$2731One-way1 change
FlixBus · FlixBus · FlixBus10:45 PM28h20Roma, Autostazione Tiburtina3:05 AMBrussels, Brussels South (Gare du Midi)$2071One-way2 changes
FlixBus · FlixBus · FlixBus7:45 AM28h35Roma, Autostazione Tiburtina12:20 PMBrussels, Brussels South (Gare du Midi)$3191One-way2 changes
FlixBus · FlixBus · FlixBus1:05 PM28h50Roma, Autostazione (Metro Anagnina)5:55 PMBrussels, Brussels South (Gare du Midi)$2581One-way2 changes
Travel Information
Compare coach and flight for Rome to Brussels
Omio recommends booking the flight as it is the most popular option from Rome to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 3h 6m. In case you are seeking to minimise your carbon footprint the coach is your best bet as it emits only 1.2 - 2.9kg. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $410.
Distance: 1174 km
Compare bus with
| Coach | Most popular Flight | Train |
|---|---|---|
$138 Average Price | $120 Average Price Cheapest | $410 Average Price |
27h 1m Average total duration 26h 31m Onboard + 30m Additional time* | 6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* | 20h 34m Average total duration 20h 4m Onboard + 30m Additional time* |
1.2 - 2.9kg CO2 emissions Lowest | 3.5 - 7.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Brussels bus times
The table below shows live departures for Rome to Brussels coaches for today, Wednesday, 29 April. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:50 AM Roma, Autostazione Tiburtina | 27h55 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 29h05 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 31h25 | 7:35 PM Brussels, Brussels South (Gare du Midi) | 2 changes | |
4788 · 50327 | 3:20 PM Roma, Autostazione Tiburtina | 25h10 | 4:30 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 30h05 | 11:30 PM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 29h10 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 28h20 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 32h25 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 31h45 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 changes | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Brussels by coach or flight
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
29 Apr
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Why should you book Rome to Brussels coaches with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus, Autoservizi Salemi Srl or Itabus to find the best option for your trip from Rome to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Rome to Brussels.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus, Autoservizi Salemi Srl or Itabus to find the best option for your trip from Rome to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Rome to Brussels.
Journey information
Overview: Bus from Rome to Brussels
Buses from Rome to Brussels run on average 11 times per day, taking around 26h 31m. Cheap bus tickets for this journey start at $82 but you can travel from only $21 by flight.
The earliest coach runs at 00:10, the last at 23:55. The fastest coach covers the 1174 km distance in 25h 10m.
Distance 1174 km |
Average bus duration 26h 31m |
Cheapest ticket price $82 |
Buses per day 11 |
Fastest bus 25h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Mon |
Best time to book 49 days |
Bus providers: FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus from Rome to BrusselsYou can travel by bus between Rome to Brussels with FlixBus, BlaBlaCar Bus, Autoservizi Salemi Srl, Itabus for as low as $21. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar Bus
Autoservizi Salemi Srl
FAQs: Rome to Brussels coach
Find answers to the most common questions about traveling from Rome to Brussels by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Important Stations and Airports in Rome and Brussels
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Most popular bus connections from Rome
More options for your journey from Rome to Brussels
Here are some other resources that might have the information you need


