The cheapest and fastest coaches from Lyon to Brussels
Cheapest price
$66
Average price
$86
Fastest journey
7 h 40 m
Average duration
8 h 20 m
Buses per day
17
Distance
569 km
The best way to find a cheap coach ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Lyon to Brussels will cost around $86 if you buy it on the day, but you can find cheap coach tickets today for only $66.
Of the 17 buses that leave Lyon for Brussels every day 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 569 km distance in an average of 8 h 20 m but if you time it right, some buses will get you there in just 7 h 40 m .
The slowest buses will take 10 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


FlixBus
5808 · 1657




4788 · 50327Travel Information
Compare train, coach and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from $26. For those with little time consider booking a flight which can get you there in 1h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a coach costs an average of $26, and a flight costs an average of $196.
Distance: 569 km
Compare bus with
| Coach | Most popular Train | Flight |
|---|---|---|
$70 Average Price Cheapest | $161 Average Price | $354 Average Price |
9h 52m Average total duration 9h 22m Onboard + 30m Additional time* | 4h 21m Average total duration 3h 51m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 1h 59m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Brussels bus times
The table below shows live departures for Lyon to Brussels coaches for today, Saturday, 15 November. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:10 am Lyon, Perrache Bus Station | 13h20 | 10:30 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
5130 · 50335 | 9:45 am Lyon, Perrache Bus Station | 11h45 | 9:30 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
58074 · 50337 | 11:00 am Lyon, Perrache Bus Station | 11h35 | 10:35 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus | 8:30 pm Lyon, Perrache Bus Station | 10h45 | 7:15 am Brussels, Brussels South (Gare du Midi) | 0 changesdirect | |
FlixBus · FlixBus | 11:50 pm Lyon, Perrache Bus Station | 11h30 | 11:20 am Brussels, Brussels South (Gare du Midi) | 1 change | |
5808 · 1657 | 12:00 am Lyon, Perrache Bus Station | 11h00 | 11:00 am Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 12:45 am Lyon, Perrache Bus Station | 11h55 | 12:40 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 1:15 am Lyon, Perrache Bus Station | 13h35 | 2:50 pm Brussels, Gare Du Midi | 1 change | |
FlixBus · FlixBus | 3:00 am Lyon, Perrache Bus Station | 11h35 | 2:35 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 4:25 am Lyon, Perrache Bus Station | 12h30 | 4:55 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
4788 · 50327 | 5:20 am Lyon, Perrache Bus Station | 10h10 | 3:30 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
83134 · 50331 | 7:35 am Lyon, Perrache Bus Station | 11h10 | 6:45 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 7:40 am Lyon, Perrache Bus Station | 12h10 | 7:50 pm Brussels, Brussels South (Gare du Midi) | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
16 Nov
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Journey information
Overview: Bus from Lyon to Brussels
Buses from Lyon to Brussels run on average 18 times per day, taking around 9h 22m. Cheap bus tickets for this journey start at $26 if you book in advance.
There are 3 coaches per day. The earliest coach runs at 00:05, the last at 23:55. The fastest coach covers the 569 km distance in 9h 40m.
Distance 569 km |
Average bus duration 9h 22m |
Cheapest ticket price $26 |
Buses per day 18 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Lyon to BrusselsYou can travel by bus between Lyon to Brussels with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as $26. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Lyon to Brussels coach
Find answers to the most common questions about traveling from Lyon to Brussels by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

When departing from Lyon, you have various coach station options to start your route from including Lyon, Perrache Bus Station and Lyon, Gare Perrache. When arriving in Brussels, you can end your route in coach stations like Brussels, Brussels South (Gare du Midi) and Bruxelles, Gare du Nord.
Passengers board the coach most frequently from Lyon, Perrache Bus Station, which is located around away from the city centre, and they get off the coach at Brussels, Brussels South (Gare du Midi), located away from the city centre.
To find the cheapest bus tickets for your trip from Lyon to Brussels, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Important Stations and Airports in Lyon and Brussels
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:00
- Free Wi-Fi
- Available outside the main terminal.
- Elevators, ramps
- Available in the station.
- Bus: 272, 471 Train: IC, S2, S4
Most popular bus connections from Lyon
More options for your journey from Lyon to Brussels
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