The cheapest and fastest coaches from Prague to Brussels
Cheapest price
60S$
Average price
73S$
Fastest journey
12 h
Average duration
14 h 32 m
Buses per day
14
Distance
717 km
The best way to find a cheap coach ticket from Prague to Brussels is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Prague to Brussels will cost around 73S$ if you buy it on the day, but you can find cheap coach tickets today for only 60S$.
Of the 14 buses that leave Prague for Brussels every day 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct buses cover the 717 km distance in an average of 14 h 32 m but if you time it right, some buses will get you there in just 12 h .
The slowest buses will take 16 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Prague -> London)6:00 PM12h00Praha, ÚAN Florenc6:00 AMBrussels, Brussels South (Gare du Midi)60 S$1One-way0 changes
FlixBus · FlixBus11:05 AM14h40Praha, ÚAN Florenc1:45 AMBrussels, Brussels South (Gare du Midi)61 S$1One-way1 change
FlixBus · FlixBus9:50 PM16h05Praha, Na Knížecí1:55 PMBrussels, Brussels South (Gare du Midi)66 S$1One-way1 change
FlixBus · FlixBus · FlixBus8:25 PM17h30Praha, Zličín1:55 PMBrussels, Brussels South (Gare du Midi)67 S$1One-way2 changes
FlixBus11:05 PM14h50Praha, ÚAN Florenc1:55 PMBrussels, Brussels South (Gare du Midi)68 S$1One-way0 changes
(Prague -> London)6:00 PM12h00Praha, ÚAN Florenc6:00 AMBrussels, Brussels South (Gare du Midi)60 S$1One-way0 changes
FlixBus · FlixBus11:05 AM14h40Praha, ÚAN Florenc1:45 AMBrussels, Brussels South (Gare du Midi)61 S$1One-way1 change
FlixBus11:05 PM14h50Praha, ÚAN Florenc1:55 PMBrussels, Brussels South (Gare du Midi)68 S$1One-way0 changes
FlixBus4:15 PM15h05Praha, ÚAN Florenc7:20 AMBrussels, Brussels South (Gare du Midi)82 S$1One-way0 changes
FlixBus · FlixBus9:50 PM16h05Praha, Na Knížecí1:55 PMBrussels, Brussels South (Gare du Midi)66 S$1One-way1 change
Travel Information
Compare train, coach and flight for Prague to Brussels
Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the coach with prices starting from 40S$. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a coach costs an average of 40S$, and a flight costs an average of 22S$.
Distance: 717 km
Compare bus with
| Coach | Most popular Flight | Train |
|---|---|---|
69S$ Average Price Cheapest | 127S$ Average Price | 101S$ Average Price |
15h 24m Average total duration 14h 54m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 3h 21m Onboard + 3h 0m Additional time* | 12h 20m Average total duration 11h 50m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | 2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Brussels bus times
The table below shows live departures for Prague to Brussels coaches for today, Thursday, 18 June. You can also manually refresh the results below to see updated coach journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
FlixBus | 4:15 PM Praha, ÚAN Florenc | 15h05 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 0 changesdirect | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 19h00 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 6:00 PM Praha, ÚAN Florenc | 18h25 | 12:25 PM Brussels, Avenue des Magnolias (King Baudouin) | 1 change | |
30513 · 1466 | 7:00 PM Praha, ÚAN Florenc | 18h30 | 1:30 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 16h05 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus | 11:05 PM Praha, ÚAN Florenc | 14h50 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 0 changesdirect | |
| Friday, 19 June | |||||
FlixBus · FlixBus · FlixBus | 9:10 AM Praha, Na Knížecí | 16h35 | 1:45 AM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus · FlixBus | 9:55 AM Praha, Zličín | 17h30 | 3:25 AM Brussels, Brussels South (Gare du Midi) | 2 changes | |
FlixBus · FlixBus | 10:55 AM Praha, Na Knížecí | 16h30 | 3:25 AM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 11:05 AM Praha, ÚAN Florenc | 14h40 | 1:45 AM Brussels, Brussels South (Gare du Midi) | 1 change | |
FlixBus · FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 18h30 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 1 change | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Brussels by train, coach or flight
Compare train, coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
18 Jun
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01 Jul
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03 Jul
04 Jul
05 Jul
06 Jul
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08 Jul
Why should you book Prague to Brussels coaches with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Brussels.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Brussels.
Journey information
Overview: Bus from Prague to Brussels
Buses from Prague to Brussels run on average 15 times per day, taking around 14h 54m. Cheap bus tickets for this journey start at 40S$ but you can travel from only 13S$ by train.
There are 2 coaches per day. The earliest coach runs at 00:10, the last at 23:50. The fastest coach covers the 717 km distance in 12h 0m.
Distance 717 km |
Average bus duration 14h 54m |
Cheapest ticket price 40S$ |
Buses per day 15 |
Direct buses 2 |
Fastest bus 12h 0m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Sept |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 84 days |
Bus providers: FlixBus, BlaBlaCar Bus from Prague to BrusselsYou can travel by bus between Prague to Brussels with FlixBus, BlaBlaCar Bus for as low as 13S$. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Prague to Brussels coach
Find answers to the most common questions about traveling from Prague to Brussels by coach. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest coach, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Important Stations and Airports in Prague and Brussels
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Most popular bus connections from Prague
More options for your journey from Prague to Brussels
Here are some other resources that might have the information you need



