Journey information
Overview: Santiago to Antofagasta flight
Flights from Santiago to Antofagasta depart on average 25 times per day, taking around 2h 5m. Cheap flight tickets for this journey start at $22 if you book in advance.
There are 14 flights per day. The earliest flight runs at 00:14, the last at 23:58. The fastest flight covers the 1091 km distance in 1h 59m. October is the cheapest month to fly.
Distance 1091 km |
Average flight duration 2h 5m |
Cheapest ticket price $22 |
Flights per day 25 |
Direct flights 14 |
Fastest flight 1h 59m |
Cheapest month to travel October |
First flight 00:14 |
Last flight 23:58 |
The cheapest and fastest flights from Santiago to Antofagasta
Cheapest price
$22
Average price
$126
Fastest journey
2 h 1 m
Average duration
2 h 4 m
Flights per day
5
Distance
1091 km
The best way to find a cheap flight ticket from Santiago to Antofagasta is to book your journey as far in advance as possible and to avoid travelling at rush hour.
The average ticket from Santiago to Antofagasta will cost around $126 if you buy it on the day, but you can find cheap flight tickets today for only $22.
Of the 5 flights that leave Santiago for Antofagasta every day 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
These direct flights cover the 1091 km distance in an average of 2 h 4 m but if you time it right, some flights will get you there in just 2 h 1 m .
The slowest flights will take 2 h 7 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare coach and flight for Santiago to Antofagasta
Omio recommends booking the flight as it is the most popular option from Santiago to Antofagasta among Omio's users. If you are prioritising price take the coach with prices starting from $32. For those with little time consider booking a flight which can get you there in 2h 5m. The ticket price range depends on the travel mode: a coach costs an average of $32, and a flight costs an average of $22.
Distance: 1091 km
Compare flight with
Most popular Flight | Coach |
|---|---|
$105 Average Price | $51 Average Price Cheapest |
5h 5m Average total duration Fastest 2h 5m Onboard + 3h 0m Additional time* | 17h 58m Average total duration 17h 28m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Santiago to Antofagasta flight times
The table below shows live departures for Santiago to Antofagasta flights for today, Monday, 23 February. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Changes | Tickets |
|---|---|---|---|---|---|
H2294 | 9:26 pm Santiago | 2h01 | 11:27 pm Antofagasta | 0 changesdirect | |
LA2696 · LA2373 | 9:30 pm Santiago | 10h00 | 7:30 am Antofagasta | 1 change | |
LA360 | 9:52 pm Santiago | 2h01 | 11:53 pm Antofagasta | 0 changesdirect | |
LA344 | 10:01 pm Santiago | 2h01 | 12:02 am Antofagasta | 0 changesdirect | |
LA362 | 11:09 pm Santiago | 2h01 | 1:10 am Antofagasta | 0 changesdirect | |
LA342 | 11:35 pm Santiago | 2h01 | 1:36 am Antofagasta | 0 changesdirect | |
LA2430 · LA2373 | 11:50 pm Santiago | 7h40 | 7:30 am Antofagasta | 1 change | |
LA352 | 11:58 pm Santiago | 2h01 | 1:59 am Antofagasta | 0 changesdirect | |
| Tuesday, 24 February | |||||
![]() | 8:11 am Santiago | 2h05 | 10:16 am Antofagasta | 0 changesdirect | |
![]() | 8:16 am Santiago | 2h01 | 10:17 am Antofagasta | 0 changesdirect | |
![]() | 9:00 am Santiago | 2h07 | 11:07 am Antofagasta | 0 changesdirect | |
![]() | 9:12 am Santiago | 2h04 | 11:16 am Antofagasta | 0 changesdirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santiago to Antofagasta by coach or flight
Compare coach and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
24 Feb
25 Feb
26 Feb
27 Feb
28 Feb
01 Mar
02 Mar
Why should you book Santiago to Antofagasta flights with Omio?
Why book with Omio vs LATAM Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for LATAM Airlines, but also compare tickets for the likes of B & H Airlines or Sky Airline to find the best option for your trip from Santiago to Antofagasta.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare LATAM Airlines with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Santiago to Antofagasta.
Why book with Omio over Kayak, Edreams or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of B & H Airlines or Sky Airline to find the best option for your trip from Santiago to Antofagasta.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Santiago to Antofagasta.
Airlines: LATAM Airlines, B & H Airlines, Sky Airline from Santiago to AntofagastaFind the best flights between Santiago to Antofagasta with Omio's travel partners LATAM Airlines, B & H Airlines, Sky Airline from $22. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
LATAM Airlines
Sky Airline
B & H Airlines
FAQs: Santiago to Antofagasta flights
Find answers to the most common questions about traveling from Santiago to Antofagasta by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Antofagasta, this guide helps you travel smarter and with confidence.

popular airports
Important Stations and Airports in Santiago and Antofagasta
- Free Wi-Fi available throughout the airport.
- Shops include duty-free and local Chilean products, located in both terminals.
- Parking available in several lots, approximately 1.7€ (CLP 1,500) per hour.
- Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby include Holiday Inn Santiago Airport, within walking distance.
- Showers available in VIP lounges; access may require a lounge pass or fee.
- Several lounges available, including LATAM and American Airlines lounges.
- Lost and Found located in the arrivals area.
- Car rental services available from major companies like Hertz and Avis.
- Bus Centropuerto, Pajaritos Station, 19 km
- Free Wi-Fi available throughout the airport.
- Shops include duty-free and local souvenir stores, located in the departures area.
- Parking available near the terminal, approximately 1€ per hour.
- Several restaurants and cafes are located in the main terminal, offering local and intertiol cuisine.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport, including accessible facilities.
- Lounge available for premium passengers and members, offering refreshments and comfortable seating.
- Lost and Found services are located near the main information desk.
- Car rental services are available from major providers like Hertz and Avis, located in the arrivals area.
- Bus 124, Aeropuerto stop, 26 km

